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Antimicrobial activity and chemical investigation of Brazilian Drosera.
abstract
The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa.
source
Ferreira DT, Andrei CC, Saridakis HO, Faria Tde J, Vinhato E, Carvalho KE, Daniel JF, Machado SL, Saridakis DP, Braz-Filho R. Mem Inst Oswaldo Cruz. 2004, 99: 753-755.
link
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15654434
標題
巴西的毛氈苔其抗菌活性及化學研究
摘要
我們以金黃色葡萄球菌(ATCC 25923)、腸球菌(ATCC23212)、綠膿桿菌(ATCC27853)、大腸桿菌(ATCC11229)、霍亂沙門氏菌(ATCC10708)、克雷白氏肺炎菌(ATCC13883)和白色念珠菌(從人上分離出來的種類)，來測試取自於巴西的毛氈苔(D. communis、D. montana var. montana、D. brevifolia、D. villosa var. graomogolensis、D. villosa var. villosa、Drosera sp. 1，和Drosera sp. 2 )的三種不同萃取物(己烷類、乙酸乙酯、甲醇)的抗菌活性。我們觀察到D. communis和D. montana var. montana的乙酸乙酯萃取物具有較好的抗菌活性。來自D. communis、D. montana var. montana和D. brevifolia的植物化學分析可得到5-hydroxy-2-methyl-1,4-naphthoquinone (礬松素)；D. communis和D. villosa var. villosa可分離出長鍊脂肪族碳氫化合物，從D. communis可分離出長鍊脂肪醇類和羧酸類混合物，從D. villosa var. villosa可分離出3b-O-acetylaleuritolic acid。
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2006/01/16 09:23am 
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